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Pet Wellbeing Milk Thistle for Cats - Supports Liver Health, Protects Liver - Glycerin-Based Natural Herbal Supplement - 2 oz (59 ml)

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Dosage should be given on an empty stomach with at least two doses and preferably 3-4 dose intervals to increase bioavailability. Do NOT sprinkle milk thistle on food. Get empty gel caps (size 0) at a health food store, put the amount you want to give in a gel cap, coat the gel cap lightly with butter and pill him with it. Milk Thistle is a natural supplement, well-known for helping with liver support in cats, dogs and humans alike. Results of the literature review with the set of criteria and filters. 3. Results of Literature Review 3.1. Silymarin, Silybin, Silybum marianum, Milk Thistle

If you’re using the regular enteric-coated tablets, these should not be split or crushed as it will affect the absorption as well as the dosage, so I wouldn’t do that without speaking with your vet first. You can read Peachez's Story with Milk Thistle for cats and how it helped her with cancer and liver problems.

About Denamarin for Cats

NHV’s certified organic Milk Thistle is a safe herb that is recommended and used by holistic practitioners. All of our products are all-natural and formulated by veterinarians with a focus on comprehensively supporting the health and well-being of your feline family member.

Silymarin reaches high levels in the bile and liver (it also reaches significant levels in the lungs, pancreas, prostate, and skin). It can be used in the treatment of feline hepatic lipidosis, chronic hepatitis, cholangitis (inflammation of the bile ducts), and pericholangitis (inflammation of the tissue around the bile ducts). It may be useful in preventing or treating gallstones by thinning the bile.The aim of the present paper is to provide, through a literature review of their effects, a scientific support for clinicians/nutritionists that necessitate of complementary feed to support liver function in dogs and cats. 2. Search Criteria

Despite that, well-designed clinical studies, such as randomized, double-blind, controlled trial, with an appropriate cohort of patients or adequate dosages of aforementioned compounds, tested as single agents or in combination, are scarce in veterinary medicine. Moreover, the vast majority of molecules to which “hepatoprotective” properties are attributed are mainly included and marketed as complementary feed. These are also intended as nutraceuticals, where a nutraceutical has been defined as “a food or part of a food, such as a dietary supplement, that has a medical or health benefit, including the prevention and treatment of disease” (Interview De Felice, 2011) [ 5] or as functional foods [ 6]. Interestingly, an international agreement on their definition has not yet been reached [ 6]. Twedt, D.C. (n.d.). Emerging newer liver conditions to be aware of in the dog. Colorado State University. Retrieved 2/6/2020 from https://pdfs.semanticscholar.org/96da/d6174658dc6fe146ad9115b6fceb30027c5c.pdf Denamarin may be recommended as part of a treatment plan for a variety of circumstances where the liver is involved. In cats, this can include conditions where liver enzymes are elevated on bloodwork like in cholangitis/cholangiohepatitis syndrome, hepatic lipidosis, and feline triad disease/triaditis.Our research has limitations as it looked only for some molecules, the most frequently included in veterinary complementary feed to support the liver function in dogs and cats, and it consequently failed to meet, for example, some other stimulating research articles always regarding this topic, although in healthy animals (one was an abstract) [ 49, 50] or in form of review [ 51]. In one case, SAMe was administered to healthy cats resulting, among other encouraging effects, in a positive influence on hepatic redox balance [ 50].

Recent studies have shown to moderate the pro-inflammatory cascade as well as having a beneficial effect on aiding healthy liver function.

Some patients on Denamarin long-term may also continue to benefit from administration every two to three days. This is why it is very important to follow your veterinarian’s instructions very carefully. Varzi, H.N., Esmailzadeh S., Morovvati, H., Avizeh, R., Shahriari, A., and Givi, M.E., (2007). Effect of silymarin and vitamin E on gentamicin-induced nephrotoxicity in dogs. J Vet Pharmacol Ther, 30(5):477. Abstract retrieved from https://www.ncbi.nlm.nih.gov/pubmed/17803742

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